11,276

LAS animals used in research

101

LAS active procedures

306

ESU animals used in research

21

ESU active procedures

67

PIP active projects

2,277

BIOBANC new sample donations

29

BIOBANC Projects which asked for samples (Material Transfer Service)

39

BIOBANC Projects which asked for sample processing services

9,814

UAT services performed

49

UAT user groups (internal groups/external clients)

343

USIC active clinical trials/studies

94

USIC Num. Principal investigators

244

UEB new services

62

ARO active studies

INDEX

LAB ANIMAL SERVICE (LAS)
EXPERIMENTAL SURGERY UNIT (ESU)
PRECLINICAL IMAGING PLATFORM (PIP)
BIOBANK
HIGH TECHNOLOGY UNIT (UAT)
CLINICAL RESEARCH SUPPORT UNIT (USIC)
STATISTICS AND BIOINFORMATICS UNIT (UEB)
ACADEMIC RESEARCH ORGANIZATION (ARO)

LAB ANIMAL SERVICE (LAS)

Animals used in research

10,589

Mice

687

Rats

Total number of mice and rats used for research purposes according to the spanish decree RD 53/2013 definition of experimental procedure.

Active procedures per species

84

Mice

17

Rats

Total number of experimental procedures approved by the Competent Authority (Generalitat de Catalunya).

Active procedures per area and species
Active procedures per area and species
Annual average of cages and individuals/week

2,461

Mice

108

Rats

Average number of cages per week (maximum number of animals x cage =5)

EXPERIMENTAL SURGERY UNIT (ESU)

Animals used in research

225

Rabbits

32

Sheep

49

Pigs

Total number of pigs, sheep and rabbits used for research purposes according to the spanish decree RD 53/2013 definition of experimental procedure.

Active procedures per species

4

Rabbits

6

Sheep

10

Pigs

1

Ex vivo procedures (ESU)

Active procedures per area and species
Active procedures per area and species ESU

PRECLINICAL IMAGING PLATFORM (PIP)

Optical imaging
Research Groups Acquiring
Hours
Quantification Hours Research projects
VHIR 164 6 13
Pediatric Oncology 1
Translational Research in Child and Adolescent Cancer 3
Liver diseases 3
Infectious Diseases 1
Neurovascular diseases 1
Neurodegenerative diseases 1
Biomedical Research in Urology 2
Cardiovascular Diseases 1
VHIO 439,00 28,25 20
Stem Cells and Cancer 3
Preclinical and Translational Research Program 5
Growth Factors 1
Tumor biomarkers 1
Modeling of Anti-tumor Therapies 5
Cellular Plasticity and Cancer 3
Experimental Hematology 2
External users 14 13,00 4
Total hours 617 47 37
Microct
Research Groups Studies (acquisition and analysis) Research projects
VHIR 364 4
Nephrology and Kidney Transplant 1
Pneumology 1
Liver diseases 1
Neurodegenerative diseases 1
VHIO 238 8
Stem Cells and Cancer 1
Preclinical and Translational Research Program 1
Modeling of Anti-tumor Therapies 4
Cellular Plasticity and Cancer 1
Radiomics 1
External users 373 5
Total acquisitions 975 17
Ultrasound
Research Groups Studies (acquisition and analysis) Research projects
VHIR 443 4
Neuromuscular and mitochondrial pathology 1
Neurodegenerative diseases 1
Cardiovascular Diseases 2
VHIO 284 6
Stem Cells and Cancer 4
Experimental Hematology 1
Cellular Plasticity and Cancer 1
External users 246 2
Total acquisitions 973 12

BIOBANK

Number of new sample donations
Cardiology Bank 106
Digestive Pathologies Bank 14
IMID: Immune Mediated Inflammatory Diseases 216
Immunology Bank 599
Nephrology Bank 331
Neurodegenerative Pathologies Bank 63
Neurological Tissue Bank 5
Obesity Bank 427
Pulmonar Bank 120
Sepsis Bank 63
Tumor Bank 147
Others 186
TOTAL NUMBER OF NEW SAMPLE DONATIONS 2,277
Number of Projects which have asked for sample processing services
15-corefacilities-biobank-01-2021

7

Cardiology Bank

1

Digestive Pathologies Bank

5

Immunology Bank

4

Nephrology Bank

1

Neurodegenerative Pathologies Bank

1

Neurological Tissue Bank

3

Obesity Bank

2

Pulmonary Bank

1

Sepsis Bank

2

Tumor Bank

12

Others

Number of Projects which have asked for samples (Material Transfer Service)
16-corefacilities-biobank-02-2021

3

Cardiology Bank

2

Digestive Pathologies Bank

1

Fetal Tissue Bank

1

Gestational Pathologies Bank

4

Immunology Bank

1

Nephrology Bank

4

Neurodegenerative Pathologies Bank

3

Neurological Tissue Bank

1

Pulmonary Bank

3

Obesity Bank

3

Sepsis Bank

3

Tumor Bank

HIGH TECHNOLOGY UNIT (UAT)

User groups
17-corefacilities-uat-01-02-2021.svg

39

Groups from VHIR

4

Partner Institutions

5

Public Research Organizations

2

Private Clients

Number of services performed (*)
18-corefacilities-uat-02-02-2021

490

Molecular Diagnosis

3,713

Genomics

3,354

Microscopy

1,595

Cytomics

662

Metabolomics

(*) The number of services for each platform is calculated by adding the number of units performed by each individual service within a platform. Internal and outsourced services managed by UAT are included.

Internal projects supported
Nº of supported projects % of service requests (**) % of total income (***)
Competitive funded projects 124 73.81% 83.17%
Non-competitive funded projects 44 26.19% 16.83%

(**) Calculated over the total number of service requests charged to internal projects.
(***) Calculated over the UAT total income for fees charged to internal projects.

New internal services
PLATFORM SERVICE
Metabolomics Development of different methods for detection and quantification of various endogenous metabolites and drugs in biological matrixes
Citometry

New service: Luminex Magpix (protein/RNA multiplexed analysis)

Customized design of antibody panels

Training and educational activities
Activities
qPCR-Introduction and advances (in collaboration with Thermo Fisher Scientific)
Introduction to panel design for flow citometry (in collaboration with Becton Dickinson)
A comprehensive view of microarrays and their applications in biomedical sciences (in collaboration with Thermo Fisher Scientific)
LightCycler 480_System and software (in collaboration with Roche)
Nanostring Technologies presentation: nCounter and GeoMx® Digital Spatial Profiler (in collaboration with Diagnostica Longwood/Nanostring)
Participation in the 48h OpenHouse Barcelona Festival

CLINICAL RESEARCH SUPPORT UNIT (USIC)

Clinical areas of services performed by USIC
USIC-Healthcare Platform
Active clinical trials/studies 343
Services/Units of HUVH 36
No. principal investigators 94
No. of visits 7,011
No. intravenous treatments 332
No. spaces used for monitoring/auditories/center selection visits, start-up and close-out visits 773
% clinical trials USIC-Healthcare Area/ active clinical trials in HUVH 24.9%
% of the use of healthcare spaces 70%
Request of studies for medical consultation 220
Request of studies for day hospital 43
Request of studies for support of research nurse 227
Petitions of public funded studies 54
Petitions of private funded studies 289

STATISTICS AND BIOINFORMATICS UNIT (UEB)

UEB Services by type
UEB new services by type TOTAL (€) TOTAL  (hores) TOTAL (# serveis)
Teaching activities (Courses & Personalized) 11,410.0 60 3
High Throughput Data Analysis (Bioinformatics) 25,887.9 996 13
Data Analysis for Clinical Research (Biostatistics) 26,273.4 1,011 75
Statistical & methodological consultancy services N/A 309 67
Database & applications development (REDCap ) 9,269.0 357 40
Clinical Trials data analysis 26,790.1 1,030 6
Regular Consultancy Collaborations 42,200.0 1,623 2
Budgets for grant proposals 0.0 114 38
TOTAL 141,830.4 5,499.2 244.0
UEB new services by user type* TOTAL (€) TOTAL (hours) TOTAL (num services)
Internal 87,524.0 3,366 228
External 42,900.8 1,381 46
TOTAL 130,424.8 4,747.7 274.0
Active projects with UEB collaboration
EU-PEARL
VEIS
EOSC-LIFE
COVID TASK FORCE
Unitat Transveral de dades VH-VHIR

ACADEMIC RESEARCH ORGANIZATION (ARO)

62

ARO active studies

Active studies by hospital service
19-corefacilities-aro-01-2021
Phases of the studies
20-corefacilities-aro-02-2021

4 (6.45%)

Phase I

5 (8.06%)

Phase I/II

10 (16.13%)

Phase II

15 (24.19%)

Phase III

15 (24.19%)

Phase IV

2 (3.23%)

Observational Study

10 (16.13%)

Other clinical Research

1 (1.61%)

Medical device

Clinical studies managed through networks
21-corefacilities-aro-03-2021

23 (37.10%)

SCReN

3 (4.84%)

ECRIN

36 (58.06%)

Out of networks

Promoter
22-corefacilities-aro-04-2021

6 (9.68%)

Medical Society

21 (33.87%)

VHIR

6 (9.68%)

Pharmaceutical Laboratories

25 (40.32%)

Hospital

1 (1.61%)

University

3 (4.84%)

Others

Development area
National 45
International 17
Centers participating
Unicentric 16
Multicentric 46